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2021-2024

  1. Choi JY, Gihaz S, Munshi M, Singh P, Vydyam P, Hamel P, Adams EM, Sun X, Khalimonchuk O, Fuller K, Ben Mamoun C. Vitamin B5 metabolism is essential for vacuolar and mitochondrial functions and drug detoxification in fungi. Commun Biol. 2024 Jul 23;7(1):894. doi: 10.1038/s42003-024-06595-7. PMID: 39043829; PMCID: PMC11266677.

  2. Cheng X, Baki VB, Moran M, Liu B, Yu J, Zhao M, Li Q, Riethoven JJ, Gurumurth CB, Harris EN, Sun X. Liver matrin-3 protects mice against hepatic steatosis and stress response via constitutive androstane receptor. Mol Metab. 2024Aug;86:101977. doi: 10.1016/j.molmet.2024.101977. Epub 2024 Jun 25. PMID:38936659; PMCID: PMC11267048.

  3. Cheng X, Shihabudeen Haider Ali MS, Baki VB, Moran M, Su H, Sun X. Multifaceted roles of Meg3 in cellular senescence and atherosclerosis. Atherosclerosis. 2024 May;392:117506. doi: 10.1016/j.atherosclerosis.2024.117506. Epub 2024 Mar 8. PMID: 38518516; PMCID: PMC11088985.

  4. Zambrano-Carrasco J, Zou J, Wang W, Sun X, Li J, Su H. Emerging Roles of Cullin-RING Ubiquitin Ligases in Cardiac Development. Cells. 2024 Jan 26;13(3):235. doi: 10.3390/cells13030235. PMID: 38334627; PMCID: PMC10854628.

  5. Liu B, Nguyen PL, Yu H, Li X, Wang H, Price J, Niu M, Guda C, Cheng X, Sun X, Moreau R, Ramer-Tait A, Naldrett MJ, Alvarez S, Yu J. Critical contributions of protein cargos to the functions of macrophage-derived extracellular vesicles. J Nanobiotechnology. 2023 Sep 28;21(1):352. doi: 10.1186/s12951-023-02105-9. PMID: 37770932; PMCID: PMC10537535.

  6. Wan T, Horová M, Khetrapal V, Li S, Jones C, Schacht A, Sun X, Zhang L. Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis. J Biol Chem. 2023 Jun;299(6):104777. doi: 10.1016/j.jbc.2023.104777. Epub 2023 May 2. PMID: 37142222; PMCID: PMC10245118.

  7. Kung CP, Skiba MB, Crosby EJ, Gorzelitz J, Kennedy MA, Kerr BA, Li YR, Nash S, Potiaumpai M, Kleckner AS, James DL, Coleman MF, Fairman CM, Galván GC, Garcia DO, Gordon MJ, His M, Hornbuckle LM, Kim SY, Kim TH, Kumar A, Mahé M, McDonnell KK, Moore J, Oh S, Sun X, Irwin ML. Key takeaways for knowledge expansion of early-career scientists conducting Transdisciplinary Research in Energetics and Cancer (TREC): a report from the TREC Training Workshop 2022. J Natl Cancer Inst Monogr. 2023 May 4;2023(61):149-157. doi: 10.1093/jncimonographs/lgad005. PMID: 37139978; PMCID: PMC10157760.

  8. Koga JI, Sun X, Ushio-Fukai M. Editorial: Mitochondria, metabolism and cardiovascular diseases. Front Cardiovasc Med. 2022 Aug 19;9:996739. doi: 10.3389/fcvm.2022.996739. PMID: 36061554; PMCID: PMC9437701.

  9. Yang D, Haemmig S, Chen J, McCoy M, Cheng HS, Zhou H, Pérez-Cremades D, Cheng X, Sun X, Haneo-Mejia J, Vellarikkal SK, Gupta RM, Barrera V, Feinberg MW. Endothelial cell-specific deletion of a microRNA accelerates atherosclerosis. Atherosclerosis. 2022 Jun;350:9-18. doi: 10.1016/j.atherosclerosis.2022.04.010. Epub 2022 Apr 12. PMID: 35462240; PMCID: PMC10165557.

  10. Kayashima Y, Clanton CA, Lewis AM, Sun X, Hiller S, Huynh P, Wilder J, Hagaman J, Li F, Maeda-Smithies N, Harris EN. Reduction of Stabilin-2 Contributes to a Protection Against Atherosclerosis. Front Cardiovasc Med. 2022 Mar 11;9:818662. doi: 10.3389/fcvm.2022.818662. PMID: 35360009; PMCID: PMC8963368.

  11. Cabral F, Al-Rahem M, Skaggs J, Thomas TA, Kumar N, Wu Q, Fadda P, Yu L, Robinson JM, Kim J, Pandey E, Sun X, Jarjour WN, Rajaram MVS, Harris EN, Ganesan LP. Stabilin receptors clear LPS and control systemic inflammation. iScience. 2021 Oct 25;24(11):103337. doi: 10.1016/j.isci.2021.103337. PMID: 34816100; PMCID: PMC8591421.

  12. Liu B, Li X, Yu H, Shi X, Zhou Y, Alvarez S, Naldrett MJ, Kachman SD, Ro SH, Sun X, Chung S, Jing L, Yu J. Therapeutic potential of garlic chive-derived vesicle-like nanoparticles in NLRP3 inflammasome-mediated inflammatory diseases. Theranostics. 2021 Sep 7;11(19):9311-9330. doi: 10.7150/thno.60265. PMID: 34646372; PMCID: PMC8490522.

  13. Sun X, Feinberg MW. Vascular Endothelial Senescence: Pathobiological Insights, Emerging Long Noncoding RNA Targets, Challenges and Therapeutic Opportunities. Front Physiol. 2021 Jun 16;12:693067. doi: 10.3389/fphys.2021.693067. PMID: 34220553; PMCID: PMC8242592.

  14. Cai Y, Zhang Y, Chen H, Sun XH, Zhang P, Zhang L, Liao MY, Zhang F, Xia ZY, Man RY, Feinberg MW, Leung SW. MicroRNA-17-3p suppresses NF-κB-mediated endothelial inflammation by targeting NIK and IKKβ binding protein. Acta Pharmacol Sin. 2021 Dec;42(12):2046-2057. doi: 10.1038/s41401-021-00611-w. Epub 2021 Feb 23. PMID: 33623121; PMCID: PMC8633290.

  15. Haemmig S, Hashemi Gheinani A, Zaromytidou M, Siasos G, Coskun AU, Cormier MA, Gross DA, Wara AKMK, Antoniadis AP, Sun X, Sukhova GK, Welt FGP, Andreou I, Whatling C, Gan LM, Wikström J, Edelman ER, Libby P, Stone PH, Feinberg MW. Novel Lesional Transcriptional Signature Separates Atherosclerosis With and Without Diabetes in Yorkshire Swine and Humans. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1487-1503. doi: 10.1161/ATVBAHA.121.315896. Epub 2021 Feb 11. PMID: 33567868; PMCID: PMC7990701.

  16. Cheng X, Shihabudeen Haider Ali MS, Moran M, Viana MP, Schlichte SL, Zimmerman MC, Khalimonchuk O, Feinberg MW, Sun X. Long non-coding RNA Meg3 deficiency impairs glucose homeostasis and insulin signaling by inducingcellular senescence of hepatic endothelium in obesity. Redox Biol. 2021 Apr;40:101863. doi: 10.1016/j.redox.2021.101863. Epub 2021 Jan 19. PMID: 33508742; PMCID: PMC7844131.

  17. Yang D, Haemmig S, Zhou H, Pérez-Cremades D, Sun X, Chen L, Li J, Haneo-Mejia J, Yang T, Hollan I, Feinberg MW. Methotrexate attenuates vascular inflammation through an adenosine-microRNA-dependent pathway. Elife. 2021 Jan 8;10:e58064. doi: 10.7554/eLife.58064. PMID: 33416495; PMCID: PMC7840179.

2017-2020

  1. Kim H, Jeon BT, Kim IM, Bennett SJ, Lorch CM, Viana MP, Myers JF, Trupp CJ, Whipps ZT, Kundu M, Chung S, Sun X, Khalimonchuk O, Lee J, Ro SH. Sestrin2 Phosphorylation by ULK1 Induces Autophagic Degradation of Mitochondria Damaged by Copper-Induced Oxidative Stress. Int J Mol Sci. 2020 Aug 25;21(17):6130. doi: 10.3390/ijms21176130. PMID: 32854424; PMCID: PMC7504119.

  2. Sun X, Harris EN. New aspects of hepatic endothelial cells in physiology and nonalcoholic fatty liver disease. Am J Physiol Cell Physiol. 2020 Jun 1;318(6):C1200-C1213. doi: 10.1152/ajpcell.00062.2020. Epub 2020 May 6. PMID: 32374676; PMCID: PMC7311747.

  3. Haemmig S, Yang D, Sun X, Das D, Ghaffari S, Molinaro R, Chen L, Deng Y, Freeman D, Moullan N, Tesmenitsky Y, Wara AKMK, Simion V, Shvartz E, Lee JF, Yang T, Sukova G, Marto JA, Stone PH, Lee WL, Auwerx J, Libby P, Feinberg MW. Long noncoding RNA SNHG12 integrates a DNA-PK-mediated DNA damage response and vascular senescence. Sci Transl Med. 2020 Feb 19;12(531):eaaw1868. doi: 10.1126/scitranslmed.aaw1868. PMID: 32075942.

  4. Arumugam R, Yalaka B, Massilamany C, Haider Ali MSS, Lasrado N, Jayaraja S, Riethoven JJ, Sun X, Reddy J. An evidence for surface expression of an immunogenic epitope of sarcoplasmic/endoplasmic reticulum calcium-ATPase2a on antigen-presenting cells from naive mice in the mediation of autoimmune myocarditis. Immunobiology. 2020 Mar;225(2):151896. doi: 10.1016/j.imbio.2019.12.005. Epub 2019 Dec 13. PMID: 31870642; PMCID: PMC7198334.

  5. Moran M, Cheng X, Shihabudeen Haider Ali MS, Wase N, Nguyen N, Yang W, Zhang C, DiRusso C, Sun X. Transcriptome analysis-identified long noncoding RNA CRNDE in maintaining endothelial cell proliferation, migration, and tube formation. Sci Rep. 2019 Dec 20;9(1):19548. doi: 10.1038/s41598-019-56030-9. PMID: 31863035; PMCID: PMC6925215.

  6. Shihabudeen Haider Ali MS, Cheng X, Moran M, Haemmig S, Naldrett MJ, Alvarez S, Feinberg MW, Sun X. LncRNA Meg3 protects endothelial function by regulating the DNA damage response. Nucleic Acids Res. 2019 Feb 20;47(3):1505-1522. doi: 10.1093/nar/gky1190. PMID: 30476192; PMCID: PMC6379667.

  7. Sun X, Haider Ali MSS, Moran M. The role of interactions of long non-coding RNAs and heterogeneous nuclear ribonucleoproteins in regulating cellular functions. Biochem J. 2017 Aug 11;474(17):2925-2935. doi: 10.1042/BCJ20170280. PMID: 28801479; PMCID: PMC5553131.

  8. Zhang Y, Sun X, Icli B, Feinberg MW. Emerging Roles for MicroRNAs in Diabetic Microvascular Disease: Novel Targets for Therapy. Endocr Rev. 2017 Apr1;38(2):145-168. doi: 10.1210/er.2016-1122. PMID: 28323921; PMCID: PMC5460677.

2016 and before (selected)

  1. Sun X, Lin J, Zhang Y, Kang S, Belkin N, Wara AK, Icli B, Hamburg NM, Li D, Feinberg MW. MicroRNA-181b Improves Glucose Homeostasis and Insulin Sensitivity by Regulating Endothelial Function in White Adipose Tissue. Circ Res. 2016 Mar 4;118(5):810-21. doi: 10.1161/CIRCRESAHA.115.308166. Epub 2016 Jan 7. PMID: 26830849; PMCID: PMC4779381.

  2. Sun X, Feinberg MW. MicroRNA-management of lipoprotein homeostasis. Circ Res. 2014 Jun 20;115(1):2-6. doi: 10.1161/CIRCRESAHA.114.304228. PMID: 24951757; PMCID: PMC4083235.

  3. Sun X, He S, Wara AKM, Icli B, Shvartz E, Tesmenitsky Y, Belkin N, Li D, Blackwell TS, Sukhova GK, Croce K, Feinberg MW. Systemic delivery of
    microRNA-181b inhibits nuclear factor-κB activation, vascular inflammation, and atherosclerosis in apolipoprotein E-deficient mice. Circ Res. 2014 Jan 3;114(1):32-40. doi: 10.1161/CIRCRESAHA.113.302089. Epub 2013 Oct 1. PMID: 24084690; PMCID: PMC4051320.

  4. Sun X, Icli B, Wara AK, Belkin N, He S, Kobzik L, Hunninghake GM, Vera MP; MICU Registry; Blackwell TS, Baron RM, Feinberg MW. MicroRNA-181b regulates NF-κB-mediated vascular inflammation. J Clin Invest. 2012 Jun;122(6):1973-90. doi: 10.1172/JCI61495. Epub 2012 May 24. PMID: 22622040; PMCID: PMC3366408.

  5. Sun XH, Flynn DC, Castranova V, Millecchia LL, Beardsley AR, Liu J. Identification of a novel domain at the N terminus of caveolin-1 that controls
    rear polarization of the protein and caveolae formation. J Biol Chem. 2007 Mar 9;282(10):7232-41. doi: 10.1074/jbc.M607396200. Epub 2007 Jan 8. PMID: 17213184.

  6. Sun XH, Tan L, Li CY, Tong C, Fan J, Li P, Zhu YS. A novel gene delivery system targeting urokinase receptor. Acta Biochim Biophys Sin (Shanghai). 2004 Jul;36(7):485-91. doi: 10.1093/abbs/36.7.485. PMID: 15248023.

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